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KMID : 1191520190240010001
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Journal of Korean Traditional Oncology
2019 Volume.24 No. 1 p.1 ~ p.9
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A Case Report of Advanced Non-Small Cell Lung Cancer Patient Treated with Samchilchoongcho-Jung in Conjunction with Alectinib
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Ko Myung-Hyun
Myong Ji-Soo
Park So-Jung
Jun Hyung-Joon
Lee Yeon-Weol
Cho Chong-Kwan
Yoo Hwa-Seung
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Abstract
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Objective: The purpose of this study is to report the clinical effectiveness of advanced non-small cell lung cancer (NSCLC) with Samchilchoongcho-Jung (HAD-B1) in conjunction with Alectinib.
Methods: The patient was diagnosed with Anaplastic lymphoma kinase (ALK) mutated (2+) non-small cell lung cancer adenocarcinoma stage IV, suffering from edema of lower extremities, dyspnea, pleural effusion, general weakness, insomnia. The patient being treated with Alectinib was treated with Samchilchoongcho-Jung (HAD-B1) for disease control and symptom management. The clinical outcomes were measured by National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Numeral rating scale (NRS) and Eastern Cooperative Oncology Group (ECOG).
Results: After treatment, dyspnea and edema of lower extremities was relieved from NRS 7 to 5, and 6 to 1 respectively. And ECOG score of the patient was improved from grade 3 to 2. During and after treatment, we didn't find any severe toxicities on laboratory findings.
Conclusion: This case study suggests that Samchilchoongcho-Jung (HAD-B1) may improve symptom relief and life quality of NSCLC patient in conjunction with Alectinib.
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KEYWORD
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Non-small cell lung cancer, adenocarcinoma, ALK mutated, Herbal Medicine, Quality of Life, Alectinib, pleural effusion
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